VEGFR1–mediated pericyte ablation links VEGF and PlGF to cancer-associated retinopathy

VEGF coordinates complex regulation of cellular regeneration and interactions between endothelial and perivascular cells; dysfunction of the VEGF signaling system leads to retinopathy. Here, we show that systemic delivery of VEGF and placental growth factor (PlGF) by protein implantation, tumors, an...

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Main Authors: Cao, Renhai, Xue, Yuan, Hedlund, Eva-Maria, Zhong, Zhaodong, Tritsaris, Katerina, Tondelli, Barbara, Lucchini, Franco, Zhu, Zhenping, Dissing, Steen, Cao, Yihai
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818941/
https://ncbi.nlm.nih.gov/pubmed/20080765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911661107
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