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Adenosine-to-inosine RNA editing by ADAR1 is essential for normal murine erythropoiesis
Adenosine deaminases that act on RNA (ADARs) convert adenosine residues to inosine in double-stranded RNA. In vivo, ADAR1 is essential for the maintenance of hematopoietic stem/progenitors. Whether other hematopoietic cell types also require ADAR1 has not been assessed. Using erythroid- and myeloid-...
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| Udgivet i: | Exp Hematol |
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| Main Authors: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5035604/ https://ncbi.nlm.nih.gov/pubmed/27373493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2016.06.250 |
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