CXCL12-induced neurotoxicity critically depends on NMDA receptor-gated and l-type Ca(2+) channels upstream of p38 MAPK

BACKGROUND: The chemokine receptor CXCR4 (CD184) and its natural ligand CXCL12 contribute to many physiological processes, including decisions about cell death and survival in the central nervous system. In addition, CXCR4 is a co-receptor for human immunodeficiency virus (HIV)-1 and mediates the ne...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Neuroinflammation
Main Authors: Sanchez, Ana B., Medders, Kathryn E., Maung, Ricky, Sánchez-Pavón, Paloma, Ojeda-Juárez, Daniel, Kaul, Marcus
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035480/
https://ncbi.nlm.nih.gov/pubmed/27664068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0724-2
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker