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CXCL12-induced neurotoxicity critically depends on NMDA receptor-gated and l-type Ca(2+) channels upstream of p38 MAPK
BACKGROUND: The chemokine receptor CXCR4 (CD184) and its natural ligand CXCL12 contribute to many physiological processes, including decisions about cell death and survival in the central nervous system. In addition, CXCR4 is a co-receptor for human immunodeficiency virus (HIV)-1 and mediates the ne...
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| Gepubliceerd in: | J Neuroinflammation |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BioMed Central
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5035480/ https://ncbi.nlm.nih.gov/pubmed/27664068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0724-2 |
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