Characterization of the Cytochrome P450 Epoxyeicosanoid Pathway in Non-alcoholic Steatohepatitis

Non-alcoholic steatohepatitis (NASH) is an emerging public health problem without effective therapies. Cytochrome P450 (CYP) epoxygenases metabolize arachidonic acid into bioactive epoxyeicosatrienoic acids (EETs), which have potent anti-inflammatory and protective effects. However, the functional r...

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Detalhes bibliográficos
Publicado no:Prostaglandins Other Lipid Mediat
Main Authors: Wells, Michael A., Vendrov, Kimberly C., Edin, Matthew L., Ferslew, Brian C., Zha, Weibin, Nguyen, Bobbie K.H., Church, Rachel J., Lih, Fred B., DeGraff, Laura M., Brouwer, Kim L.R., Barritt, A. Sidney, Zeldin, Darryl C., Lee, Craig R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035202/
https://ncbi.nlm.nih.gov/pubmed/27401401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2016.07.002
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