Characterization of the Cytochrome P450 Epoxyeicosanoid Pathway in Non-alcoholic Steatohepatitis

Non-alcoholic steatohepatitis (NASH) is an emerging public health problem without effective therapies. Cytochrome P450 (CYP) epoxygenases metabolize arachidonic acid into bioactive epoxyeicosatrienoic acids (EETs), which have potent anti-inflammatory and protective effects. However, the functional r...

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Dades bibliogràfiques
Publicat a:Prostaglandins Other Lipid Mediat
Autors principals: Wells, Michael A., Vendrov, Kimberly C., Edin, Matthew L., Ferslew, Brian C., Zha, Weibin, Nguyen, Bobbie K.H., Church, Rachel J., Lih, Fred B., DeGraff, Laura M., Brouwer, Kim L.R., Barritt, A. Sidney, Zeldin, Darryl C., Lee, Craig R.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035202/
https://ncbi.nlm.nih.gov/pubmed/27401401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2016.07.002
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