The Cytochrome P450 Epoxygenase Pathway Regulates the Hepatic Inflammatory Response in Fatty Liver Disease

Fatty liver disease is an emerging public health problem without effective therapies, and chronic hepatic inflammation is a key pathologic mediator in its progression. Cytochrome P450 (CYP) epoxygenases metabolize arachidonic acid to biologically active epoxyeicosatrienoic acids (EETs), which have p...

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Bibliografiske detaljer
Main Authors: Schuck, Robert N., Zha, Weibin, Edin, Matthew L., Gruzdev, Artiom, Vendrov, Kimberly C., Miller, Tricia M., Xu, Zhenghong, Lih, Fred B., DeGraff, Laura M., Tomer, Kenneth B., Jones, H. Michael, Makowski, Liza, Huang, Leaf, Poloyac, Samuel M., Zeldin, Darryl C., Lee, Craig R.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195706/
https://ncbi.nlm.nih.gov/pubmed/25310404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110162
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