The Cytochrome P450 Epoxygenase Pathway Regulates the Hepatic Inflammatory Response in Fatty Liver Disease

Fatty liver disease is an emerging public health problem without effective therapies, and chronic hepatic inflammation is a key pathologic mediator in its progression. Cytochrome P450 (CYP) epoxygenases metabolize arachidonic acid to biologically active epoxyeicosatrienoic acids (EETs), which have p...

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Main Authors: Schuck, Robert N., Zha, Weibin, Edin, Matthew L., Gruzdev, Artiom, Vendrov, Kimberly C., Miller, Tricia M., Xu, Zhenghong, Lih, Fred B., DeGraff, Laura M., Tomer, Kenneth B., Jones, H. Michael, Makowski, Liza, Huang, Leaf, Poloyac, Samuel M., Zeldin, Darryl C., Lee, Craig R.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195706/
https://ncbi.nlm.nih.gov/pubmed/25310404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110162
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