The Cytochrome P450 Epoxygenase Pathway Regulates the Hepatic Inflammatory Response in Fatty Liver Disease

Fatty liver disease is an emerging public health problem without effective therapies, and chronic hepatic inflammation is a key pathologic mediator in its progression. Cytochrome P450 (CYP) epoxygenases metabolize arachidonic acid to biologically active epoxyeicosatrienoic acids (EETs), which have p...

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Autors principals: Schuck, Robert N., Zha, Weibin, Edin, Matthew L., Gruzdev, Artiom, Vendrov, Kimberly C., Miller, Tricia M., Xu, Zhenghong, Lih, Fred B., DeGraff, Laura M., Tomer, Kenneth B., Jones, H. Michael, Makowski, Liza, Huang, Leaf, Poloyac, Samuel M., Zeldin, Darryl C., Lee, Craig R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195706/
https://ncbi.nlm.nih.gov/pubmed/25310404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110162
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