Characterization of the Cytochrome P450 Epoxyeicosanoid Pathway in Non-alcoholic Steatohepatitis

Non-alcoholic steatohepatitis (NASH) is an emerging public health problem without effective therapies. Cytochrome P450 (CYP) epoxygenases metabolize arachidonic acid into bioactive epoxyeicosatrienoic acids (EETs), which have potent anti-inflammatory and protective effects. However, the functional r...

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Publié dans:Prostaglandins Other Lipid Mediat
Auteurs principaux: Wells, Michael A., Vendrov, Kimberly C., Edin, Matthew L., Ferslew, Brian C., Zha, Weibin, Nguyen, Bobbie K.H., Church, Rachel J., Lih, Fred B., DeGraff, Laura M., Brouwer, Kim L.R., Barritt, A. Sidney, Zeldin, Darryl C., Lee, Craig R.
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035202/
https://ncbi.nlm.nih.gov/pubmed/27401401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2016.07.002
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