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Solid-State NMR Studies Reveal Native-like β-sheet Structures in Transthyretin amyloid

Structural characterization of amyloid rich in cross-β structures is crucial for unraveling molecular basis of protein misfolding and amyloid formation associated with a wide range of human disorders. Elucidation of the β-sheet structure in non-crystalline amyloid has, however, remained an enormous...

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Dettagli Bibliografici
Pubblicato in:Biochemistry
Autori principali: Lim, Kwang Hun, Dasari, Anvesh K. R., Hung, Ivan, Gan, Zhehong, Kelly, Jeffery W., Wright, Peter E., Wemmer, David E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035109/
https://ncbi.nlm.nih.gov/pubmed/27589034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00649
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