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Osteoclasts promote immune suppressive microenvironment in multiple myeloma: therapeutic implication
The number and activity of osteoclasts (OCs) are strongly enhanced by myeloma cells, leading to significant bone lesions in patients with multiple myeloma (MM). Mechanisms remain elusive as to whether myeloma-supporting OCs also induce suppressive immune bone marrow (BM) microenvironment. Here, we f...
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| 發表在: | Blood |
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| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Hematology
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5034739/ https://ncbi.nlm.nih.gov/pubmed/27418644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-03-707547 |
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