Synergy of radiotherapy and PD-1 blockade in Kras-mutant lung cancer

Radiation therapy (RT), a critical modality in the treatment of lung cancer, induces direct tumor cell death and augments tumor-specific immunity. However, despite initial tumor control, most patients suffer from locoregional relapse and/or metastatic disease following RT. The use of immunotherapy i...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Herter-Sprie, Grit S., Koyama, Shohei, Korideck, Houari, Hai, Josephine, Deng, Jiehui, Li, Yvonne Y., Buczkowski, Kevin A., Grant, Aaron K., Ullas, Soumya, Rhee, Kevin, Cavanaugh, Jillian D., Neupane, Neermala Poudel, Christensen, Camilla L., Herter, Jan M., Makrigiorgos, G. Mike, Hodi, F. Stephen, Freeman, Gordon J., Dranoff, Glenn, Hammerman, Peter S., Kimmelman, Alec C., Wong, Kwok-Kin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033933/
https://ncbi.nlm.nih.gov/pubmed/27699275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87415
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