Synergy of radiotherapy and PD-1 blockade in Kras-mutant lung cancer

Radiation therapy (RT), a critical modality in the treatment of lung cancer, induces direct tumor cell death and augments tumor-specific immunity. However, despite initial tumor control, most patients suffer from locoregional relapse and/or metastatic disease following RT. The use of immunotherapy i...

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Bibliografski detalji
Izdano u:JCI Insight
Glavni autori: Herter-Sprie, Grit S., Koyama, Shohei, Korideck, Houari, Hai, Josephine, Deng, Jiehui, Li, Yvonne Y., Buczkowski, Kevin A., Grant, Aaron K., Ullas, Soumya, Rhee, Kevin, Cavanaugh, Jillian D., Neupane, Neermala Poudel, Christensen, Camilla L., Herter, Jan M., Makrigiorgos, G. Mike, Hodi, F. Stephen, Freeman, Gordon J., Dranoff, Glenn, Hammerman, Peter S., Kimmelman, Alec C., Wong, Kwok-Kin
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033933/
https://ncbi.nlm.nih.gov/pubmed/27699275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87415
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