Adjuvanted multi-epitope vaccines protect HLA-A*11:01 transgenic mice against Toxoplasma gondii

We created and tested multi-epitope DNA or protein vaccines with TLR4 ligand emulsion adjuvant (gluco glucopyranosyl lipid adjuvant in a stable emulsion [GLA-SE]) for their ability to protect against Toxoplasma gondii in HLA transgenic mice. Our constructs each included 5 of our best down-selected C...

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Bibliografiset tiedot
Julkaisussa:JCI Insight
Päätekijät: El Bissati, Kamal, Chentoufi, Aziz A., Krishack, Paulette A., Zhou, Ying, Woods, Stuart, Dubey, Jitender P., Vang, Lo, Lykins, Joseph, Broderick, Kate E., Mui, Ernest, Suzuki, Yasuhiro, Sa, Qila, Bi, Stephanie, Cardona, Nestor, Verma, Shiv K., Fraczek, Laura, Reardon, Catherine A., Sidney, John, Alexander, Jeff, Sette, Alessandro, Vedvick, Tom, Fox, Chris, Guderian, Jeffrey A., Reed, Steven, Roberts, Craig W., McLeod, Rima
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2016
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033759/
https://ncbi.nlm.nih.gov/pubmed/27699241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.85955
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