Engineering and characterization of a novel Self Assembling Protein for Toxoplasma peptide vaccine in HLA-A*11:01, HLA-A*02:01 and HLA-B*07:02 transgenic mice

Fighting smart diseases requires smart vaccines. Novel ways to present protective immunogenic peptide epitopes to human immune systems are needed. Herein, we focus on Self Assembling Protein Nanoparticles (SAPNs) as scaffolds/platforms for vaccine delivery that produce strong immune responses agains...

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Опубликовано в: :Sci Rep
Главные авторы: El Bissati, Kamal, Zhou, Ying, Paulillo, Sara M., Raman, Senthil K., Karch, Christopher P., Reed, Steve, Estes, Ashley, Estes, Amber, Lykins, Joseph, Burkhard, Peter, McLeod, Rima
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7552409/
https://ncbi.nlm.nih.gov/pubmed/33046728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73210-0
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