Engineering and characterization of a novel Self Assembling Protein for Toxoplasma peptide vaccine in HLA-A*11:01, HLA-A*02:01 and HLA-B*07:02 transgenic mice

Fighting smart diseases requires smart vaccines. Novel ways to present protective immunogenic peptide epitopes to human immune systems are needed. Herein, we focus on Self Assembling Protein Nanoparticles (SAPNs) as scaffolds/platforms for vaccine delivery that produce strong immune responses agains...

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Publicado no:Sci Rep
Main Authors: El Bissati, Kamal, Zhou, Ying, Paulillo, Sara M., Raman, Senthil K., Karch, Christopher P., Reed, Steve, Estes, Ashley, Estes, Amber, Lykins, Joseph, Burkhard, Peter, McLeod, Rima
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7552409/
https://ncbi.nlm.nih.gov/pubmed/33046728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73210-0
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