Protein nanovaccine confers robust immunity against Toxoplasma

We designed and produced a self-assembling protein nanoparticle. This self-assembling protein nanoparticle contains five CD8(+) HLA-A03-11 supertypes-restricted epitopes from antigens expressed during Toxoplasma gondii’s lifecycle, the universal CD4(+) T cell epitope PADRE, and flagellin as a scaffo...

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Bibliografische gegevens
Gepubliceerd in:NPJ Vaccines
Hoofdauteurs: El Bissati, Kamal, Zhou, Ying, Paulillo, Sara Maria, Raman, Senthil Kumar, Karch, Christopher P., Roberts, Craig W., Lanar, David E., Reed, Steve, Fox, Chris, Carter, Darrick, Alexander, Jeff, Sette, Alessandro, Sidney, John, Lorenzi, Hernan, Begeman, Ian J., Burkhard, Peter, McLeod, Rima
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627305/
https://ncbi.nlm.nih.gov/pubmed/29263879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-017-0024-6
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