Protein nanovaccine confers robust immunity against Toxoplasma

We designed and produced a self-assembling protein nanoparticle. This self-assembling protein nanoparticle contains five CD8(+) HLA-A03-11 supertypes-restricted epitopes from antigens expressed during Toxoplasma gondii’s lifecycle, the universal CD4(+) T cell epitope PADRE, and flagellin as a scaffo...

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Detalhes bibliográficos
Publicado no:NPJ Vaccines
Main Authors: El Bissati, Kamal, Zhou, Ying, Paulillo, Sara Maria, Raman, Senthil Kumar, Karch, Christopher P., Roberts, Craig W., Lanar, David E., Reed, Steve, Fox, Chris, Carter, Darrick, Alexander, Jeff, Sette, Alessandro, Sidney, John, Lorenzi, Hernan, Begeman, Ian J., Burkhard, Peter, McLeod, Rima
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627305/
https://ncbi.nlm.nih.gov/pubmed/29263879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-017-0024-6
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