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Adjuvanted multi-epitope vaccines protect HLA-A*11:01 transgenic mice against Toxoplasma gondii

We created and tested multi-epitope DNA or protein vaccines with TLR4 ligand emulsion adjuvant (gluco glucopyranosyl lipid adjuvant in a stable emulsion [GLA-SE]) for their ability to protect against Toxoplasma gondii in HLA transgenic mice. Our constructs each included 5 of our best down-selected C...

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發表在:JCI Insight
Main Authors: El Bissati, Kamal, Chentoufi, Aziz A., Krishack, Paulette A., Zhou, Ying, Woods, Stuart, Dubey, Jitender P., Vang, Lo, Lykins, Joseph, Broderick, Kate E., Mui, Ernest, Suzuki, Yasuhiro, Sa, Qila, Bi, Stephanie, Cardona, Nestor, Verma, Shiv K., Fraczek, Laura, Reardon, Catherine A., Sidney, John, Alexander, Jeff, Sette, Alessandro, Vedvick, Tom, Fox, Chris, Guderian, Jeffrey A., Reed, Steven, Roberts, Craig W., McLeod, Rima
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033759/
https://ncbi.nlm.nih.gov/pubmed/27699241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.85955
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