The Transcriptional Repressive Activity of KRAB Zinc Finger Proteins Does Not Correlate with Their Ability to Recruit TRIM28

KRAB domain Zinc finger proteins are one of the most abundant families of transcriptional regulators in higher vertebrates. The prevailing view is that KRAB domain proteins function as potent transcriptional repressors by recruiting TRIM28 and promoting heterochromatin spreading. However, the extent...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Murphy, Kristin E., Shylo, Natalia A., Alexander, Katherine A., Churchill, Angela J., Copperman, Cecilia, García-García, María J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033580/
https://ncbi.nlm.nih.gov/pubmed/27658112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163555
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