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The Transcriptional Repressive Activity of KRAB Zinc Finger Proteins Does Not Correlate with Their Ability to Recruit TRIM28

KRAB domain Zinc finger proteins are one of the most abundant families of transcriptional regulators in higher vertebrates. The prevailing view is that KRAB domain proteins function as potent transcriptional repressors by recruiting TRIM28 and promoting heterochromatin spreading. However, the extent...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:PLoS One
Main Authors: Murphy, Kristin E., Shylo, Natalia A., Alexander, Katherine A., Churchill, Angela J., Copperman, Cecilia, García-García, María J.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033580/
https://ncbi.nlm.nih.gov/pubmed/27658112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163555
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