The Transcriptional Repressive Activity of KRAB Zinc Finger Proteins Does Not Correlate with Their Ability to Recruit TRIM28

KRAB domain Zinc finger proteins are one of the most abundant families of transcriptional regulators in higher vertebrates. The prevailing view is that KRAB domain proteins function as potent transcriptional repressors by recruiting TRIM28 and promoting heterochromatin spreading. However, the extent...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Murphy, Kristin E., Shylo, Natalia A., Alexander, Katherine A., Churchill, Angela J., Copperman, Cecilia, García-García, María J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033580/
https://ncbi.nlm.nih.gov/pubmed/27658112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163555
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