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Size-dependent Toxicity of Gold Nanoparticles on Human Embryonic Stem Cells and Their Neural Derivatives

This study explores the use of human embryonic stem cells (hESCs) for assessing nanotoxicology, specifically, the effect of gold nanoparticles (AuNPs) of different core sizes (1.5 nm, 4 nm, and 14 nm) on the viability, pluripotency, neuronal differentiation, and DNA methylation of hESCs. The hESCs e...

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Dades bibliogràfiques
Publicat a:Small
Autors principals: Senut, Marie-Claude, Zhang, Yanhua, Liu, Fangchao, Sen, Arko, Ruden, Douglas M., Mao, Guangzhao
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033512/
https://ncbi.nlm.nih.gov/pubmed/26676601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.201502346
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