Transporter protein and drug-conjugated gold nanoparticles capable of bypassing the blood-brain barrier

Drug delivery to the central nervous system (CNS) is challenging due to the inability of many drugs to cross the blood-brain barrier (BBB). Here, we show that wheat germ agglutinin horse radish peroxidase (WGA-HRP) chemically conjugated to gold nanoparticles (AuNPs) can be transported to the spinal...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Zhang, Yanhua, Walker, Janelle Buttry, Minic, Zeljka, Liu, Fangchao, Goshgarian, Harry, Mao, Guangzhao
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867579/
https://ncbi.nlm.nih.gov/pubmed/27180729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25794
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