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Size-dependent Toxicity of Gold Nanoparticles on Human Embryonic Stem Cells and Their Neural Derivatives

This study explores the use of human embryonic stem cells (hESCs) for assessing nanotoxicology, specifically, the effect of gold nanoparticles (AuNPs) of different core sizes (1.5 nm, 4 nm, and 14 nm) on the viability, pluripotency, neuronal differentiation, and DNA methylation of hESCs. The hESCs e...

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Detalhes bibliográficos
Publicado no:Small
Main Authors: Senut, Marie-Claude, Zhang, Yanhua, Liu, Fangchao, Sen, Arko, Ruden, Douglas M., Mao, Guangzhao
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033512/
https://ncbi.nlm.nih.gov/pubmed/26676601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.201502346
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