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Lead Exposure Disrupts Global DNA Methylation in Human Embryonic Stem Cells and Alters Their Neuronal Differentiation

Exposure to lead (Pb) during childhood can result in learning disabilities and behavioral problems. Although described in animal models, whether Pb exposure also alters neuronal differentiation in the developing brains of exposed children is unknown. Here, we investigated the effects of physiologica...

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Bibliografische gegevens
Hoofdauteurs: Senut, Marie-Claude, Sen, Arko, Cingolani, Pablo, Shaik, Asra, Land, Susan J., Ruden, Douglas M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023291/
https://ncbi.nlm.nih.gov/pubmed/24519525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu028
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