Lead exposure induces changes in 5-hydroxymethylcytosine clusters in CpG islands in human embryonic stem cells and umbilical cord blood

Prenatal exposure to neurotoxicants such as lead (Pb) may cause stable changes in the DNA methylation (5mC) profile of the fetal genome. However, few studies have examined its effect on the DNA de-methylation pathway, specifically the dynamic changes of the 5-hydroxymethylcytosine (5hmC) profile. Th...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Epigenetics
Main Authors: Sen, Arko, Cingolani, Pablo, Senut, Marie-Claude, Land, Susan, Mercado-Garcia, Adriana, Tellez-Rojo, Martha M, Baccarelli, Andrea A, Wright, Robert O, Ruden, Douglas M
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2015
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623482/
https://ncbi.nlm.nih.gov/pubmed/26046694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2015.1050172
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares