Hsp20-Mediated Activation of Exosome Biogenesis in Cardiomyocytes Improves Cardiac Function and Angiogenesis in Diabetic Mice

Decreased heat shock protein (Hsp) expression in type 1 and type 2 diabetes has been implicated as a primary factor contributing to diabetes-induced organ damage. We recently showed that diabetic cardiomyocytes could release detrimental exosomes, which contain lower levels of Hsp20 than normal ones....

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Bibliographic Details
Published in:Diabetes
Main Authors: Wang, Xiaohong, Gu, Haitao, Huang, Wei, Peng, Jiangtong, Li, Yutian, Yang, Liwang, Qin, Dongze, Essandoh, Kobina, Wang, Yigang, Peng, Tianqing, Fan, Guo-Chang
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2016
Subjects:
Pathophysiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033265/
https://ncbi.nlm.nih.gov/pubmed/27284111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-1563
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