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Treatment of spontaneous EAE by laquinimod reduces Tfh, B cell aggregates, and disease progression
OBJECTIVE: To evaluate the influence of oral laquinimod, a candidate multiple sclerosis (MS) treatment, on induction of T follicular helper cells, development of meningeal B cell aggregates, and clinical disease in a spontaneous B cell–dependent MS model. METHODS: Experimental autoimmune encephalomy...
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Publicado no: | Neurol Neuroimmunol Neuroinflamm |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Lippincott Williams & Wilkins
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5032667/ https://ncbi.nlm.nih.gov/pubmed/27704036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000272 |
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