Laquinimod, an upcoming oral immunomodulatory agent for treatment of multiple sclerosis

Por Varrin-Doyer, Michel, Zamvil, Scott S., Schulze-Topphoff, Ulf
Publicado em 2014

Laquinimod, a Quinoline-3-Carboxamide, Induces Type II Myeloid Cells That Modulate Central Nervous System Autoimmunity

Por Schulze-Topphoff, Ulf, Shetty, Aparna, Varrin-Doyer, Michel, Molnarfi, Nicolas, Sagan, Sharon A., Sobel, Raymond A., Nelson, Patricia A., Zamvil, Scott S.
Publicado em 2012

Aquaporin 4-Specific T Cells in Neuromyelitis Optica Exhibit a Th17 Bias and Recognize Clostridium ABC Transporter

Por Varrin-Doyer, Michel, Spencer, Collin M, Schulze-Topphoff, Ulf, Nelson, Patricia A, Stroud, Robert M, C Cree, Bruce A, Zamvil, Scott S
Publicado em 2012

Glatiramer acetate treatment negatively regulates type I interferon signaling

Por Molnarfi, Nicolas, Prod'homme, Thomas, Schulze-Topphoff, Ulf, Spencer, Collin M., Weber, Martin S., Patarroyo, Juan C., Lalive, Patrice H., Zamvil, Scott S.
Publicado no Neurol Neuroimmunol Neuroinflamm (2015)

Tob1 plays a critical role in the activation of encephalitogenic T cells in CNS autoimmunity

Por Schulze-Topphoff, Ulf, Casazza, Simona, Varrin-Doyer, Michel, Pekarek, Kara, Sobel, Raymond A., Hauser, Stephen L., Oksenberg, Jorge R., Zamvil, Scott S., Baranzini, Sergio E.
Publicado em 2013

TRAIL limits excessive host immune responses in bacterial meningitis

Por Hoffmann, Olaf, Priller, Josef, Prozorovski, Timour, Schulze-Topphoff, Ulf, Baeva, Nevena, Lunemann, Jan D., Aktas, Orhan, Mahrhofer, Cordula, Stricker, Sarah, Zipp, Frauke, Weber, Joerg R.
Publicado em 2007

Treatment of spontaneous EAE by laquinimod reduces Tfh, B cell aggregates, and disease progression

Por Varrin-Doyer, Michel, Pekarek, Kara L., Spencer, Collin M., Bernard, Claude C.A., Sobel, Raymond A., Cree, Bruce A.C., Schulze-Topphoff, Ulf, Zamvil, Scott S.
Publicado no Neurol Neuroimmunol Neuroinflamm (2016)

MOG transmembrane and cytoplasmic domains contain highly stimulatory T-cell epitopes in MS

Por Varrin-Doyer, Michel, Shetty, Aparna, Spencer, Collin M., Schulze-Topphoff, Ulf, Weber, Martin S., Bernard, Claude C.A., Forsthuber, Thomas, Cree, Bruce A.C., Slavin, Anthony J., Zamvil, Scott S.
Publicado em 2014

Electrostatically Stabilized Magnetic Nanoparticles – An Optimized Protocol to Label Murine T Cells for in vivo MRI

Por Wuerfel, Eva, Smyth, Maureen, Millward, Jason M., Schellenberger, Eyk, Glumm, Jana, Prozorovski, Timour, Aktas, Orhan, Schulze-Topphoff, Ulf, Schnorr, Jörg, Wagner, Susanne, Taupitz, Matthias, Infante-Duarte, Carmen, Wuerfel, Jens
Publicado em 2011

Dimethyl fumarate treatment induces adaptive and innate immune modulation independent of Nrf2

Por Schulze-Topphoff, Ulf, Varrin-Doyer, Michel, Pekarek, Kara, Spencer, Collin M., Shetty, Aparna, Sagan, Sharon A., Cree, Bruce A. C., Sobel, Raymond A., Wipke, Brian T., Steinman, Lawrence, Scannevin, Robert H., Zamvil, Scott S.
Publicado no Proc Natl Acad Sci U S A (2016)

The ubiquitin-modifying enzyme A20 restricts the ubiquitination of RIPK3 and protects cells from necroptosis

Por Onizawa, Michio, Oshima, Shigeru, Schulze-Topphoff, Ulf, Oses-Prieto, Juan A, Lu, Timothy, Tavares, Rita, Prodhomme, Thomas, Duong, Bao, Whang, Michael I., Advincula, Rommel, Agelidis, Alex, Barrera, Julio, Wu, Hao, Burlingame, Alma, Malynn, Barbara A., Zamvil, Scott S., Ma, Averil
Publicado no Nat Immunol (2015)

Erratum: The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis

Por Onizawa, Michio, Oshima, Shigeru, Schulze-Topphoff, Ulf, Oses-Prieto, Juan A, Lu, Timothy, Tavares, Rita, Prodhomme, Thomas, Duong, Bao, Whang, Michael I, Advincula, Rommel, Agelidis, Alex, Barrera, Julio, Wu, Hao, Burlingame, Alma, Malynn, Barbara A, Zamvil, Scott S, Ma, Averil
Publicado no Nat Immunol (2015)

Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system

Por Schulze-Topphoff, Ulf, Prat, Alexandre, Prozorovski, Timour, Siffrin, Volker, Paterka, Magdalena, Herz, Josephine, Bendix, Ivo, Ifergan, Igal, Schadock, Ines, Mori, Marcelo A, Van Horssen, Jack, Schröter, Friederike, Smorodchenko, Alina, Han, May Htwe, Bader, Michael, Steinman, Lawrence, Aktas, Orhan, Zipp, Frauke
Publicado no Nat Med (2009)

MHC class II–dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies

Por Molnarfi, Nicolas, Schulze-Topphoff, Ulf, Weber, Martin S., Patarroyo, Juan C., Prod’homme, Thomas, Varrin-Doyer, Michel, Shetty, Aparna, Linington, Christopher, Slavin, Anthony J., Hidalgo, Juan, Jenne, Dieter E., Wekerle, Hartmut, Sobel, Raymond A., Bernard, Claude C.A., Shlomchik, Mark J., Zamvil, Scott S.
Publicado em 2013

Immunodominant T-cell epitopes of MOG reside in its transmembrane and cytoplasmic domains in EAE

Por Shetty, Aparna, Gupta, Sheena G., Varrin-Doyer, Michel, Weber, Martin S., Prod'homme, Thomas, Molnarfi, Nicolas, Ji, Niannian, Nelson, Patricia A., Patarroyo, Juan C., Schulze-Topphoff, Ulf, Fogal, Stephen E., Forsthuber, Thomas, Sobel, Raymond A., Bernard, Claude C.A., Slavin, Anthony J., Zamvil, Scott S.
Publicado em 2014

Autoregulation of Th1-mediated inflammation by twist1

Por Niesner, Uwe, Albrecht, Inka, Janke, Marko, Doebis, Cornelia, Loddenkemper, Christoph, Lexberg, Maria H., Eulenburg, Katharina, Kreher, Stephan, Koeck, Juliana, Baumgrass, Ria, Bonhagen, Kerstin, Kamradt, Thomas, Enghard, Philipp, Humrich, Jens Y., Rutz, Sascha, Schulze-Topphoff, Ulf, Aktas, Orhan, Bartfeld, Sina, Radbruch, Helena, Hegazy, Ahmed N., Löhning, Max, Baumgart, Daniel C., Duchmann, Rainer, Rudwaleit, Martin, Häupl, Thomas, Gitelman, Inna, Krenn, Veit, Gruen, Joachim, Sieper, Jochen, Zeitz, Martin, Wiedenmann, Bertram, Zipp, Frauke, Hamann, Alf, Janitz, Michal, Scheffold, Alexander, Burmester, Gerd R., Chang, Hyun D., Radbruch, Andreas
Publicado em 2008