Aquaporin 4-Specific T Cells in Neuromyelitis Optica Exhibit a Th17 Bias and Recognize Clostridium ABC Transporter

OBJECTIVE: Aquaporin 4 (AQP4)-specific autoantibodies in neuromyelitis optica (NMO) are immunoglobulin (Ig)G1, a T cell-dependent Ig subclass, indicating that AQP4-specific T cells participate in NMO pathogenesis. Our goal was to identify and characterize AQP4-specific T cells in NMO patients and he...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Varrin-Doyer, Michel, Spencer, Collin M, Schulze-Topphoff, Ulf, Nelson, Patricia A, Stroud, Robert M, C Cree, Bruce A, Zamvil, Scott S
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2012
Assuntos:
Rapid Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405197/
https://ncbi.nlm.nih.gov/pubmed/22807325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.23651
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados