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Dimethyl fumarate treatment induces adaptive and innate immune modulation independent of Nrf2
Dimethyl fumarate (DMF) (BG-12, Tecfidera) is a fumaric acid ester (FAE) that was advanced as a multiple sclerosis (MS) therapy largely for potential neuroprotection as it was recognized that FAEs are capable of activating the antioxidative transcription factor nuclear factor (erythroid-derived 2)-l...
Zapisane w:
Wydane w: | Proc Natl Acad Sci U S A |
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Główni autorzy: | , , , , , , , , , , , |
Format: | Artigo |
Język: | Inglês |
Wydane: |
National Academy of Sciences
2016
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4855599/ https://ncbi.nlm.nih.gov/pubmed/27078105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603907113 |
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