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TRAIL limits excessive host immune responses in bacterial meningitis

Apart from potential roles in anti-tumor surveillance, the TNF-related apoptosis-inducing ligand (TRAIL) has important regulatory functions in the host immune response. We studied antiinflammatory effects of endogenous and recombinant TRAIL (rTRAIL) in experimental meningitis. Following intrathecal...

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Detalhes bibliográficos
Main Authors: Hoffmann, Olaf, Priller, Josef, Prozorovski, Timour, Schulze-Topphoff, Ulf, Baeva, Nevena, Lunemann, Jan D., Aktas, Orhan, Mahrhofer, Cordula, Stricker, Sarah, Zipp, Frauke, Weber, Joerg R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1888568/
https://ncbi.nlm.nih.gov/pubmed/17571163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30356
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