MOG transmembrane and cytoplasmic domains contain highly stimulatory T-cell epitopes in MS

OBJECTIVE: Recently, we reported that the 218 amino acid murine full-length myelin oligodendrocyte glycoprotein (MOG) contains novel T-cell epitopes p119-132, p181-195, and p186-200, located within its transmembrane and cytoplasmic domains, and that p119-132 is its immunodominant encephalitogenic T-...

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Detalhes bibliográficos
Main Authors: Varrin-Doyer, Michel, Shetty, Aparna, Spencer, Collin M., Schulze-Topphoff, Ulf, Weber, Martin S., Bernard, Claude C.A., Forsthuber, Thomas, Cree, Bruce A.C., Slavin, Anthony J., Zamvil, Scott S.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202926/
https://ncbi.nlm.nih.gov/pubmed/25340072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000020
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