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Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks
Repair of single-ended DNA double-strand breaks (seDSBs) by homologous recombination (HR) requires the generation of a 3′ single-strand DNA overhang by exonuclease activities in a process called DNA resection. However, it is anticipated that the highly abundant DNA end-binding protein Ku sequesters...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5031800/ https://ncbi.nlm.nih.gov/pubmed/27641979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12889 |
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