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Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks
Repair of single-ended DNA double-strand breaks (seDSBs) by homologous recombination (HR) requires the generation of a 3′ single-strand DNA overhang by exonuclease activities in a process called DNA resection. However, it is anticipated that the highly abundant DNA end-binding protein Ku sequesters...
Zapisane w:
| Wydane w: | Nat Commun |
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| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group
2016
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5031800/ https://ncbi.nlm.nih.gov/pubmed/27641979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12889 |
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