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A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair

DNA double-strand breaks (DSBs) are the most toxic of all genomic insults, and pathways dealing with their signaling and repair are crucial to prevent cancer and for immune system development. Despite intense investigations, our knowledge of these pathways has been technically limited by our inabili...

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Detalhes bibliográficos
Main Authors: Britton, Sébastien, Coates, Julia, Jackson, Stephen P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734090/
https://ncbi.nlm.nih.gov/pubmed/23897892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201303073
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