ATM antagonizes NHEJ proteins assembly and DNA-ends synapsis at single-ended DNA double strand breaks

Two DNA repair pathways operate at DNA double strand breaks (DSBs): non-homologous end-joining (NHEJ), that requires two adjacent DNA ends for ligation, and homologous recombination (HR), that resects one DNA strand for invasion of a homologous duplex. Faithful repair of replicative single-ended DSB...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Britton, Sébastien, Chanut, Pauline, Delteil, Christine, Barboule, Nadia, Frit, Philippe, Calsou, Patrick
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Genome Integrity, Repair and Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515714/
https://ncbi.nlm.nih.gov/pubmed/32890395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa723
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