Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose

The arrangement of β cells within islets of Langerhans is critical for insulin release through the generation of rhythmic activity. A privileged role for individual β cells in orchestrating these responses has long been suspected, but not directly demonstrated. We show here that the β cell populatio...

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Vydáno v:Cell Metab
Hlavní autoři: Johnston, Natalie R., Mitchell, Ryan K., Haythorne, Elizabeth, Pessoa, Maria Paiva, Semplici, Francesca, Ferrer, Jorge, Piemonti, Lorenzo, Marchetti, Piero, Bugliani, Marco, Bosco, Domenico, Berishvili, Ekaterine, Duncanson, Philip, Watkinson, Michael, Broichhagen, Johannes, Trauner, Dirk, Rutter, Guy A., Hodson, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031557/
https://ncbi.nlm.nih.gov/pubmed/27452146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.06.020
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