NLRP3 inflammasome is expressed and regulated in human islets

NRLP3 inflammasome is a protein complex involved in the maturation of IL1β. In the onset of type 1 diabetes as well as in islet transplantation, IL-1β is one of the cytokines involved in the recruitment of immune cells in islets and eventually in islet destruction. Whether IL-1β is produced by islet...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Lebreton, Fanny, Berishvili, Ekaterine, Parnaud, Géraldine, Rouget, Caroline, Bosco, Domenico, Berney, Thierry, Lavallard, Vanessa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018156/
https://ncbi.nlm.nih.gov/pubmed/29941940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0764-x
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