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NLRP3 Inflammasome is Activated in Rat Pancreatic Islets by Transplantation and Hypoxia

Hypoxia, IL-1β production and oxidative stress are involved in islet graft dysfunction and destruction. However, the link between these events has not yet been determined in transplanted islets. The goal of this study was to determine whether NLRP3 inflammasome is responsible for IL-1β production an...

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Publicado en:Sci Rep
Main Authors: Lavallard, Vanessa, Cottet-Dumoulin, David, Wassmer, Charles-Henri, Rouget, Caroline, Parnaud, Géraldine, Brioudes, Estelle, Lebreton, Fanny, Bellofatto, Kevin, Berishvili, Ekaterine, Berney, Thierry, Bosco, Domenico
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181690/
https://ncbi.nlm.nih.gov/pubmed/32332867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64054-9
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