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NLRP3 Inflammasome is Activated in Rat Pancreatic Islets by Transplantation and Hypoxia

Hypoxia, IL-1β production and oxidative stress are involved in islet graft dysfunction and destruction. However, the link between these events has not yet been determined in transplanted islets. The goal of this study was to determine whether NLRP3 inflammasome is responsible for IL-1β production an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Lavallard, Vanessa, Cottet-Dumoulin, David, Wassmer, Charles-Henri, Rouget, Caroline, Parnaud, Géraldine, Brioudes, Estelle, Lebreton, Fanny, Bellofatto, Kevin, Berishvili, Ekaterine, Berney, Thierry, Bosco, Domenico
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181690/
https://ncbi.nlm.nih.gov/pubmed/32332867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64054-9
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