ADCY5 Couples Glucose to Insulin Secretion in Human Islets

Single nucleotide polymorphisms (SNPs) within the ADCY5 gene, encoding adenylate cyclase 5, are associated with elevated fasting glucose and increased type 2 diabetes (T2D) risk. Despite this, the mechanisms underlying the effects of these polymorphic variants at the level of pancreatic β-cells rema...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Hodson, David J., Mitchell, Ryan K., Marselli, Lorella, Pullen, Timothy J., Gimeno Brias, Silvia, Semplici, Francesca, Everett, Katy L., Cooper, Dermot M.F., Bugliani, Marco, Marchetti, Piero, Lavallard, Vanessa, Bosco, Domenico, Piemonti, Lorenzo, Johnson, Paul R., Hughes, Stephen J., Li, Daliang, Li, Wen-Hong, Shapiro, A.M. James, Rutter, Guy A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Diabetes Association 2014
Предметы:
Islet Studies
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141364/
https://ncbi.nlm.nih.gov/pubmed/24740569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1607
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы