ADCY5 Couples Glucose to Insulin Secretion in Human Islets

Single nucleotide polymorphisms (SNPs) within the ADCY5 gene, encoding adenylate cyclase 5, are associated with elevated fasting glucose and increased type 2 diabetes (T2D) risk. Despite this, the mechanisms underlying the effects of these polymorphic variants at the level of pancreatic β-cells rema...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Hodson, David J., Mitchell, Ryan K., Marselli, Lorella, Pullen, Timothy J., Gimeno Brias, Silvia, Semplici, Francesca, Everett, Katy L., Cooper, Dermot M.F., Bugliani, Marco, Marchetti, Piero, Lavallard, Vanessa, Bosco, Domenico, Piemonti, Lorenzo, Johnson, Paul R., Hughes, Stephen J., Li, Daliang, Li, Wen-Hong, Shapiro, A.M. James, Rutter, Guy A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Diabetes Association 2014
Ämnen:
Islet Studies
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141364/
https://ncbi.nlm.nih.gov/pubmed/24740569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1607
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk