Palmitate Activates Autophagy in INS-1E β-Cells and in Isolated Rat and Human Pancreatic Islets

We have investigated the in vitro effects of increased levels of glucose and free fatty acids on autophagy activation in pancreatic beta cells. INS-1E cells and isolated rat and human pancreatic islets were incubated for various times (from 2 to 24 h) at different concentrations of glucose and/or pa...

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Detalhes bibliográficos
Main Authors: Martino, Luisa, Masini, Matilde, Novelli, Michela, Beffy, Pascale, Bugliani, Marco, Marselli, Lorella, Masiello, Pellegrino, Marchetti, Piero, De Tata, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341371/
https://ncbi.nlm.nih.gov/pubmed/22563482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036188
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