Palmitate Activates Autophagy in INS-1E β-Cells and in Isolated Rat and Human Pancreatic Islets

We have investigated the in vitro effects of increased levels of glucose and free fatty acids on autophagy activation in pancreatic beta cells. INS-1E cells and isolated rat and human pancreatic islets were incubated for various times (from 2 to 24 h) at different concentrations of glucose and/or pa...

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Main Authors: Martino, Luisa, Masini, Matilde, Novelli, Michela, Beffy, Pascale, Bugliani, Marco, Marselli, Lorella, Masiello, Pellegrino, Marchetti, Piero, De Tata, Vincenzo
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341371/
https://ncbi.nlm.nih.gov/pubmed/22563482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036188
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