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Optical control of insulin release using a photoswitchable sulfonylurea
Sulfonylureas are widely prescribed for the treatment of type 2 diabetes mellitus (T2DM). Through their actions on ATP-sensitive potassium (K(ATP)) channels, sulfonylureas boost insulin release from the pancreatic beta cell mass to restore glucose homeostasis. A limitation of these compounds is the...
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| Autores principales: | , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Pub. Group
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4208094/ https://ncbi.nlm.nih.gov/pubmed/25311795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6116 |
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