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Altered Cerebrospinal Fluid Proteins in Smith-Lemli-Opitz Syndrome Patients

Smith-Lemli-Opitz syndrome (SLOS) is an autosomal recessive, multiple malformation syndrome with neurocognitive impairment. SLOS arises from mutations in the 7-dehydrocholesterol reductase gene which results in impaired enzymatic conversion of 7-dehydrocholesterol to cholesterol. In the current work...

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Detalles Bibliográficos
Publicado en:Am J Med Genet A
Main Authors: Cologna, Stephanie M., Shieh, Christine, Toth, Cynthia L., Cougnoux, Antony, Burkert, Kathryn R., Bianconi, Simona E., Wassif, Christopher A., Porter, Forbes D.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028137/
https://ncbi.nlm.nih.gov/pubmed/27148958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.37720
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