Pathological classification of human iPSC-derived neural stem/progenitor cells towards safety assessment of transplantation therapy for CNS diseases

The risk of tumorigenicity is a hurdle for regenerative medicine using induced pluripotent stem cells (iPSCs). Although teratoma formation is readily distinguishable, the malignant transformation of iPSC derivatives has not been clearly defined due to insufficient analysis of histology and phenotype...

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Bibliografiset tiedot
Julkaisussa:Mol Brain
Päätekijät: Sugai, Keiko, Fukuzawa, Ryuji, Shofuda, Tomoko, Fukusumi, Hayato, Kawabata, Soya, Nishiyama, Yuichiro, Higuchi, Yuichiro, Kawai, Kenji, Isoda, Miho, Kanematsu, Daisuke, Hashimoto-Tamaoki, Tomoko, Kohyama, Jun, Iwanami, Akio, Suemizu, Hiroshi, Ikeda, Eiji, Matsumoto, Morio, Kanemura, Yonehiro, Nakamura, Masaya, Okano, Hideyuki
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2016
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027634/
https://ncbi.nlm.nih.gov/pubmed/27642008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0265-8
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