Fail-Safe System against Potential Tumorigenicity after Transplantation of iPSC Derivatives

Human induced pluripotent stem cells (iPSCs) are promising in regenerative medicine. However, the risks of teratoma formation and the overgrowth of the transplanted cells continue to be major hurdles that must be overcome. Here, we examined the efficacy of the inducible caspase-9 (iCaspase9) gene as...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Itakura, Go, Kawabata, Soya, Ando, Miki, Nishiyama, Yuichiro, Sugai, Keiko, Ozaki, Masahiro, Iida, Tsuyoshi, Ookubo, Toshiki, Kojima, Kota, Kashiwagi, Rei, Yasutake, Kaori, Nakauchi, Hiromitsu, Miyoshi, Hiroyuki, Nagoshi, Narihito, Kohyama, Jun, Iwanami, Akio, Matsumoto, Morio, Nakamura, Masaya, Okano, Hideyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355810/
https://ncbi.nlm.nih.gov/pubmed/28262544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.02.003
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