Fail-Safe System against Potential Tumorigenicity after Transplantation of iPSC Derivatives

Human induced pluripotent stem cells (iPSCs) are promising in regenerative medicine. However, the risks of teratoma formation and the overgrowth of the transplanted cells continue to be major hurdles that must be overcome. Here, we examined the efficacy of the inducible caspase-9 (iCaspase9) gene as...

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Detalhes bibliográficos

Principais autores:	Go Itakura, Soya Kawabata, Miki Ando, Yuichiro Nishiyama, Keiko Sugai, Masahiro Ozaki, Tsuyoshi Iida, Toshiki Ookubo, Kota Kojima, Rei Kashiwagi, Kaori Yasutake, Hiromitsu Nakauchi, Hiroyuki Miyoshi, Narihito Nagoshi, Jun Kohyama, Akio Iwanami, Morio Matsumoto, Masaya Nakamura, Hideyuki Okano
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2017-03-01
coleção:	Stem Cell Reports
Assuntos:	induced pluripotent stem cells (iPSCs) iCaspase9 iPSC-derived neural stem/progenitor cells (iPSC-NS/PCs) spinal cord injury
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2213671117300474
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