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MutS regulates access of the error-prone DNA polymerase Pol IV to replication sites: a novel mechanism for maintaining replication fidelity

Translesion DNA polymerases (Pol) function in the bypass of template lesions to relieve stalled replication forks but also display potentially deleterious mutagenic phenotypes that contribute to antibiotic resistance in bacteria and lead to human disease. Effective activity of these enzymes requires...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Margara, Lucía M., Fernández, Marisa M., Malchiodi, Emilio L., Argaraña, Carlos E., Monti, Mariela R.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027486/
https://ncbi.nlm.nih.gov/pubmed/27257069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw494
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