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MutS regulates access of the error-prone DNA polymerase Pol IV to replication sites: a novel mechanism for maintaining replication fidelity

Translesion DNA polymerases (Pol) function in the bypass of template lesions to relieve stalled replication forks but also display potentially deleterious mutagenic phenotypes that contribute to antibiotic resistance in bacteria and lead to human disease. Effective activity of these enzymes requires...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Margara, Lucía M., Fernández, Marisa M., Malchiodi, Emilio L., Argaraña, Carlos E., Monti, Mariela R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027486/
https://ncbi.nlm.nih.gov/pubmed/27257069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw494
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